Diseases >HIV

Abacavir

Human Immunodeficiency Virus (HIV)

HIV is the virus that caused autoimmune deficiency syndrome (AIDS). Over 35 million people are infected with the virus and it is at epidemic proportions in Sub-Sarah Africa were 10% of childhood deaths are attributed to the disease (UNAIDS, 2010 Mendell). Currently there is no cure for the disease, but combinations of drugs known as highly active antiretroviral therapy (HAART) have helped managed the disease in the developed world.

An important aspect of HAART treatment is managing the in vivo therapeutic and toxic levels of the antiretroviral drugs. During my years in clinical research at Consolidated Laboratory Services (CLS), my efforts focused on therapeutic drug monitoring (TDM) to help minimize the toxicity of antiretrovirals while ensuring low blood titer levels of HIV.